Brenca inherited one copy of the variant we tested
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BRN 45920
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Health Summary
Brenca inherited one variant that you should learn more about.
Dilated Cardiomyopathy, DCM1
What does this result mean?
Research indicates that this genetic variant is not likely to increase the risk that Brenca will develop this condition.
Scientific Basis
Dogs with Brenca’s breed have been included in research studies or have had follow-up by our experts that indicate that this genetic variant is not likely to increase the risk of Brenca developing clinical disease.
Impact on Breeding
This genetic result should not be the primary factor in your breeding decisions.
What is Dilated Cardiomyopathy, DCM1?
DCM is the most common acquired heart disease of adult dogs. The heart has two heavily muscled ventricles that pump blood away from the heart. This disease causes progressive weakening of the ventricles by reducing the muscle mass, which causes the ventricles to dilate. Dilated ventricles do not contract and circulate oxygenated blood well, which eventually leads to heart failure.
Breed-Relevant Genetic Conditions
Von Willebrand Disease Type I, Type I vWD (VWF)
Identified in Dutch Shepherds
Variant not detected
Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII (GUSB Exon 3, German Shepherd Variant)
Identified in Dutch Shepherds
Variant not detected
Spongy Degeneration with Cerebellar Ataxia 1 (KCNJ10)
Identified in Dutch Shepherds
Variant not detected
Spongy Degeneration with Cerebellar Ataxia 2 (ATP1B2)
Identified in Dutch Shepherds
Variant not detected
Inflammatory Myopathy (SLC25A12)
Identified in Dutch Shepherds
Variant not detected
Additional Genetic Conditions
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What is a linkage test?
DNA sequences that are close together on a chromosome tend to be inherited together. Because of this, we can use genetic variation surrounding a specific variant (i.e. "linked" to it) to infer the presence or absence of a variant that is associated with a health condition or trait.
Linkage tests are not as predictive of your dog’s true genotype as direct assays, which we use on most other genetic conditions we test for.
Traits
Explore the genetics behind your dog’s appearance and size.
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Coat Color
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Other Coat Traits
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Other Body Features
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Body Size
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.