Sabe inherited both copies of the variant we tested
No Dogs Available
It looks like you don’t have any dogs on your account yet. Activate a kit now!
No bio has been provided yet
Place of Birth
Yucca Valley, CA, USA
Current Location
Yucca Valley, California, USA
This dog has been viewed and been given 0 wags
Registration
American Kennel Club
(AKC):
Start a conversation! Message this dog’s owner.
Explore
Changes to this dog’s profile
- On 4/4/2019 changed name from "SoCal's Crazy For "Sable"" to "Sabe"
Our policy is that each dog’s profile should accurately portray the dog to which the genetic reports belong.
To help ensure adherence to this policy, we show here any changes that have been made to the name or handle (web address) of this dog.
If you believe that this profile is in violation of this policy, you may contact us to report it.
Health Summary
Sabe is at increased risk for one genetic health condition.
And inherited one variant that you should learn more about.
Intervertebral Disc Disease (Type I)
What does this result mean?
Follow-up by our experts indicates that this genetic variant is associated with an increase to Sabe’s risk for developing Intervertebral Disc Disease (Type I).
Scientific Basis
Research studies for this variant have been based on dogs of other breeds. While dogs with similar breeds to Sabe have not yet been the focus of research studies, our data indicates that Sabe is likely to be at increased risk.
Impact on Breeding
While further investigation is warranted to determine the clinical presentation and penetrance in Sabe’s breed, we recommend taking this genetic result into account when making breeding decisions.
What is Intervertebral Disc Disease (Type I)?
Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.
ALT Activity
Sabe inherited both copies of the variant we tested
Why is this important to your vet?
Sabe has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Sabe's ALT activity above their current, healthy, ALT activity. As an increase above Sabe’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.
What is ALT Activity?
Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.
Breed-Relevant Genetic Conditions
Persistent Mullerian Duct Syndrome, PMDS (AMHR2)
Identified in Miniature Schnauzers
Variant not detected
Myotonia Congenita (CLCN1 Exon 7, Miniature Schnauzer Variant)
Identified in Miniature Schnauzers
Variant not detected
Additional Genetic Conditions
Explore
What is a linkage test?
DNA sequences that are close together on a chromosome tend to be inherited together. Because of this, we can use genetic variation surrounding a specific variant (i.e. "linked" to it) to infer the presence or absence of a variant that is associated with a health condition or trait.
Linkage tests are not as predictive of your dog’s true genotype as direct assays, which we use on most other genetic conditions we test for.
Traits
Explore the genetics behind your dog’s appearance and size.
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Coat Color
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Other Coat Traits
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Other Body Features
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Body Size
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.