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Rose inherited both copies of the variant we tested
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Health Summary
Rose has one variant that you should let your vet know about.
ALT Activity
Why is this important to your vet?
Rose has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Rose's ALT activity above their current, healthy, ALT activity. As an increase above Rose’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.
What is ALT Activity?
Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.
Breed-Relevant Genetic Conditions
10 variants not detected
Progressive Retinal Atrophy, prcd (PRCD Exon 1)
Identified in Golden Retrievers
Variant not detected
Golden Retriever Progressive Retinal Atrophy 1, GR-PRA1 (SLC4A3)
Identified in Golden Retrievers
Variant not detected
Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2 (TTC8)
Identified in Golden Retrievers
Variant not detected
Neuronal Ceroid Lipofuscinosis 5, NCL 5 (CLN5 Exon 4 Deletion, Golden Retriever Variant)
Identified in Golden Retrievers
Variant not detected
Degenerative Myelopathy, DM (SOD1A)
Identified in Golden Retrievers
Variant not detected
Muscular Dystrophy (DMD, Golden Retriever Variant)
Identified in Golden Retrievers
Variant not detected
Congenital Myasthenic Syndrome, CMS (COLQ, Golden Retriever Variant)
Identified in Golden Retrievers
Variant not detected
Dystrophic Epidermolysis Bullosa (COL7A1, Golden Retriever Variant)
Identified in Golden Retrievers
Variant not detected
Ichthyosis, ICH1 (PNPLA1, Golden Retriever Variant)
Identified in Golden Retrievers
Variant not detected
Osteogenesis Imperfecta (COL1A1, Golden Retriever Variant)
Identified in Golden Retrievers
Variant not detected
Additional Genetic Conditions
231 variants not detected
