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“Retta”
Retta

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Health Summary

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Retta inherited one variant that you should learn more about.

Dilated Cardiomyopathy, DCM1

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Retta inherited one copy of the variant we tested

What does this result mean?

Research indicates that this genetic variant is not likely to increase the risk that Retta will develop this condition.

Scientific Basis

Dogs with Retta’s breeds have been included in research studies or have had follow-up by our experts that indicate that this genetic variant is not likely to increase the risk of Retta developing clinical disease.

Impact on Breeding

This genetic result should not be the primary factor in your breeding decisions.

What is Dilated Cardiomyopathy, DCM1?

DCM is the most common acquired heart disease of adult dogs. The heart has two heavily muscled ventricles that pump blood away from the heart. This disease causes progressive weakening of the ventricles by reducing the muscle mass, which causes the ventricles to dilate. Dilated ventricles do not contract and circulate oxygenated blood well, which eventually leads to heart failure.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity (ABCB1)

Identified in Australian Shepherds and Collies

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Australian Shepherds

Collie Eye Anomaly (NHEJ1)

Identified in Australian Shepherds and Collies

Day Blindness (CNGB3 Deletion, Alaskan Malamute Variant)

Identified in Australian Shepherds

Canine Multifocal Retinopathy, cmr1 (BEST1 Exon 2)

Identified in Australian Shepherds

Hereditary Cataracts (HSF4 Exon 9, Australian Shepherd Variant)

Identified in Australian Shepherds

Urate Kidney & Bladder Stones (SLC2A9)

Identified in Australian Shepherds

Neuronal Ceroid Lipofuscinosis 6, NCL 6 (CLN6 Exon 7, Australian Shepherd Variant)

Identified in Australian Shepherds

Neuronal Ceroid Lipofuscinosis 8, NCL 8 (CLN8, Australian Shepherd Variant)

Identified in Australian Shepherds

Recurrent Inflammatory Pulmonary Disease, RIPD (AKNA, Rough Collie Variant)

Identified in Collies

Degenerative Myelopathy, DM (SOD1A)

Identified in Australian Shepherds and Collies

Craniomandibular Osteopathy, CMO (SLC37A2)

Identified in Australian Shepherds

β-Mannosidosis (MANBA Exon 16, Mixed-Breed Variant)

Identified in Mixed-breed dogs

Junctional Epidermolysis Bullosa (LAMB3 Exon 11, Australian Shepherd Variant)

Identified in Australian Shepherds

Additional Genetic Conditions

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Traits

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Coat Color

Coat Color

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