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Prancer

“He is the son of Gibson and Nora”

Place of Birth

Salem, MO, USA

Current Location

Salem, MO, USA

From

Salem, MO, USA

This dog has been viewed and been given 0 wags

Registration

American Kennel Club (AKC):

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Changes to this dog’s profile
  • On 11/30/2021 changed handle from "yellow151" to "prancer151"
  • On 11/30/2021 changed name from "Yellow" to "Prancer"

Health Summary

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Prancer inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Urate Kidney & Bladder Stones

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Prancer inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Prancer’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Prancer is unlikely to develop this condition due to this variant because he only has one copy of the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of his offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Urate Kidney & Bladder Stones?

This condition causes kidney and bladder stones composed of urate. In most dogs, uric acid is converted to allantoin, an inert substance that is then excreted in the urine. Dogs with HUU have defects in the pathway that converts uric acid to allantoin. As such, uric acid builds up, crystallizes and forms urate stones in the kidney and bladder. Uric acid is an intermediate of purine metabolism. While hyperuricemia in other species (including humans) can lead to painful conditions such as gout, dogs do not develop systemic signs of hyperuricemia.

ALT Activity

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Prancer inherited both copies of the variant we tested

Why is this important to your vet?

Prancer has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Prancer's ALT activity above their current, healthy, ALT activity. As an increase above Prancer’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Additional Genetic Conditions

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