Venn diagram

Compare your dogs to Juliette Select one to begin:

“Juliette”
Poesia’s Sweet Talkin’ Woman

Doberman Pinscher

“She’s adorable”

This dog has been viewed and been given 0 wags

Registration

American Kennel Club (AKC): WS76430405

Genetic Breed Result

Loading...

Doberman Pinscher

Doberman Pinschers are a strong and athletic breed that are built to guard and protect.

Learn More

Loading...

Start a conversation! Message this dog’s owner.

Loading...

Explore

Health Summary

danger icon

Juliette is at increased risk for one genetic health condition.

Dilated Cardiomyopathy, DCM2

danger icon

Juliette inherited one copy of the variant we tested

How to interpret this result

Juliette has one copy of a variant in the TTN gene associated with increased risk for DCM in the American Doberman Pinscher. This variant, also referred to as DCM2, is inherited in a dominant manner, meaning having one or two copies of this variant is thought to confer the same amount of risk. However, the variant is thought to have incomplete penetrance: That is, not all dogs with this variant will ultimately show signs of DCM. Moreover, the impact of this variant in other breeds of dog besides the Doberman has yet to be fully understood. However, if your veterinarian thinks Juliette shows signs of having DCM based on their diagnostic testing, you now have the opportunity to discuss early treatment. Please consult with your veterinarian regarding a diagnostic and treatment plan for Juliette.

What is Dilated Cardiomyopathy, DCM2?

DCM is the most common acquired heart disease of adult dogs. The heart has two heavily muscled ventricles that pump blood away from the heart. This disease causes progressive weakening of the ventricles by reducing the muscle mass, which causes the ventricles to dilate. Dilated ventricles do not contract and circulate oxygenated blood well, which eventually leads to heart failure.

Breed-Relevant Genetic Conditions

good icon

Von Willebrand Disease Type I, Type I vWD (VWF)

Identified in Doberman Pinschers

Deafness and Vestibular Syndrome of Dobermans, DVDob, DINGS (MYO7A)

Identified in Doberman Pinschers

Narcolepsy (HCRTR2 Intron 4, Doberman Pinscher Variant)

Identified in Doberman Pinschers

Dilated Cardiomyopathy, DCM1 (PDK4, Doberman Pinscher Variant 1)

Identified in Doberman Pinschers

Ehlers Danlos (ADAMTS2, Doberman Pinscher Variant)

Identified in Doberman Pinschers

Additional Genetic Conditions

good icon

Explore

Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

Loading...

Explore

Through Juliette’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1e

Haplotype

A226

Map

A1e

Poesia’s Sweet Talkin’ Woman’s Haplogroup

This female lineage likely stems from some of the original Central Asian wolves that were domesticated into modern dogs starting about 15,000 years ago. It seemed to be a fairly rare dog line for most of dog history until the past 300 years, when the lineage seemed to “explode” out and spread quickly. What really separates this group from the pack is its presence in Alaskan village dogs and Samoyeds. It is possible that this was an indigenous lineage brought to the Americas from Siberia when people were first starting to make that trip themselves! We see this lineage pop up in overwhelming numbers of Irish Wolfhounds, and it also occurs frequently in popular large breeds like Bernese Mountain Dogs, Saint Bernards and Great Danes. Shetland Sheepdogs are also common members of this maternal line, and we see it a lot in Boxers, too. Though it may be all mixed up with European dogs thanks to recent breeding events, its origins in the Americas makes it a very exciting lineage for sure!

A226

Poesia’s Sweet Talkin’ Woman’s Haplotype

Part of the large A1e haplogroup, we have spotted this haplotype in village dogs in Central and South America and Papua New Guinea. Among the 10 breeds we have detected it in, we see it most frequently in Border Collies, Doberman Pinschers, and Samoyeds.

Irish Wolfhounds are a consistent carrier of A1e.

Loading...

Explore

The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Juliette inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Juliette is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

Loading...

Explore