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“Mora”
GCH URO1 CVK Mora Kasif

Anatolian Shepherd Dog

“Mora is a UKC registered Kangal Dog.”

Place of Birth

Wisconsin, USA

Current Location

Wisconsin, USA

From

Wisconsin, USA

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Registration

United Kennel Club (UKC): P967-494

Genetic Breed Result

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Anatolian Shepherd Dog

The Anatolian Shepherd Dog is a native of Turkey, where he was developed as a shepherd’s companion and livestock guardian. He was bred to resemble the size and color of the livestock he defended so predators would not detect him among the flock. Sometimes called the Anatolian Karabash Dog, he’s a fiercely loyal guard dog and a large, impressive dog breed, weighing 120 to 150 pounds at maturity.

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Changes to this dog’s profile
  • On 11/14/2022 changed name from "Mora" to "CVK Mora Kasif"

Health Summary

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Mora inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Von Willebrand Disease Type I, Type I vWD

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Mora inherited one copy of the variant we tested

What does this result mean?

We do not know whether this increases the risk that Mora will develop Von Willebrand Disease Type I, Type I vWD.

Scientific Basis

Research studies for this variant have been based on dogs of other breeds. Not enough dogs with Mora's breed have been studied to know whether or not this variant will increase Mora's risk of developing this disease.

Impact on Breeding

Research into the clinical impact of this variant is ongoing. We recommend tracking this genetic result and incidence of Von Willebrand Disease Type I, Type I vWD in your breeding program and related dogs.

What is Von Willebrand Disease Type I, Type I vWD?

Von Willebrand Disease (vWD) is a type of coagulopathy, a disorder of blood clotting. vWD is characterized into three types based on clinical severity, serum levels of vWF, and vWF multimer composition. Dogs with Type I vWD have low vWF levels, normal multimer composition, and variable clinical signs.

ALT Activity

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Mora inherited one copy of the variant we tested

Why is this important to your vet?

Mora has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Mora has this genotype, as ALT is often used as an indicator of liver health and Mora is likely to have a lower than average resting ALT activity. As such, an increase in Mora’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

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Through Mora’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1c

Haplotype

A297

Map

A1c

CVK Mora Kasif’s Haplogroup

About 15,000 years ago in Central Asia, females from this lineage were some of the wolves domesticated as the original dogs. Since then, dogs from this lineage traveled through the Middle East to Africa, where they became some of the African village dogs and basenjis, which are a native African breed of dog. There are also still pockets of dogs with this lineage that remained in Asia or places along the route to Africa, such as India. This lineage has also been found in the Borzoi, a Russian dog breed.

A297

CVK Mora Kasif’s Haplotype

Part of the large A1c haplogroup, we have spotted this haplotype in Borzoi dogs and village dogs in Turkey.

The presence of A1c in a Borzoi indicates a deep history of this lineage in Eurasia

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Mora inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Mora is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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