Louis Vuitton - Biewer Terrier inherited one copy of the variant we tested
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Changes to this dog’s profile
- On 6/30/2023 changed handle from "louisvuittonbiemale" to "louisvuitton6676"
- On 6/30/2023 changed name from "LOUIS VUITTON BIE MALE" to "Louis Vuitton - Biewer Terrier"
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Health Summary
Louis Vuitton - Biewer Terrier is at increased risk for one genetic health condition.
And inherited three variants that you should learn more about.
Intervertebral Disc Disease (Type I)
What does this result mean?
Follow-up by our experts indicates that this genetic variant is associated with an increase to Louis Vuitton - Biewer Terrier’s risk for developing Intervertebral Disc Disease (Type I).
Scientific Basis
Research studies for this variant have been based on dogs of other breeds. While dogs with similar breeds to Louis Vuitton - Biewer Terrier have not yet been the focus of research studies, our data indicates that Louis Vuitton - Biewer Terrier is likely to be at increased risk.
Impact on Breeding
While further investigation is warranted to determine the clinical presentation and penetrance in Louis Vuitton - Biewer Terrier’s breed, we recommend taking this genetic result into account when making breeding decisions.
What is Intervertebral Disc Disease (Type I)?
Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.
Dilated Cardiomyopathy, DCM1
Louis Vuitton - Biewer Terrier inherited one copy of the variant we tested
What does this result mean?
Research indicates that this genetic variant is not likely to increase the risk that Louis Vuitton - Biewer Terrier will develop this condition.
Scientific Basis
Dogs with Louis Vuitton - Biewer Terrier’s breed have been included in research studies or have had follow-up by our experts that indicate that this genetic variant is not likely to increase the risk of Louis Vuitton - Biewer Terrier developing clinical disease.
Impact on Breeding
This genetic result should not be the primary factor in your breeding decisions.
What is Dilated Cardiomyopathy, DCM1?
DCM is the most common acquired heart disease of adult dogs. The heart has two heavily muscled ventricles that pump blood away from the heart. This disease causes progressive weakening of the ventricles by reducing the muscle mass, which causes the ventricles to dilate. Dilated ventricles do not contract and circulate oxygenated blood well, which eventually leads to heart failure.
Bald Thigh Syndrome
Louis Vuitton - Biewer Terrier inherited one copy of the variant we tested
What does this result mean?
This variant should not impact Louis Vuitton - Biewer Terrier’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Louis Vuitton - Biewer Terrier is unlikely to develop this condition due to this variant because he only has one copy of the variant.
Impact on Breeding
Your dog carries this variant and will pass it on to ~50% of his offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.
What is Bald Thigh Syndrome?
A cosmetic condition common to sighthounds characterized by hair loss on the thighs. It is caused by a structural abnormality of the hair follicle.
ALT Activity
Louis Vuitton - Biewer Terrier inherited one copy of the variant we tested
Why is this important to your vet?
Louis Vuitton - Biewer Terrier has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Louis Vuitton - Biewer Terrier has this genotype, as ALT is often used as an indicator of liver health and Louis Vuitton - Biewer Terrier is likely to have a lower than average resting ALT activity. As such, an increase in Louis Vuitton - Biewer Terrier’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.
What is ALT Activity?
Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.
Breed-Relevant Genetic Conditions
Progressive Retinal Atrophy, prcd (PRCD Exon 1)
Identified in Biewer Terriers
Variant not detected
Primary Lens Luxation (ADAMTS17)
Identified in Biewer Terriers
Variant not detected
Additional Genetic Conditions
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What is a linkage test?
DNA sequences that are close together on a chromosome tend to be inherited together. Because of this, we can use genetic variation surrounding a specific variant (i.e. "linked" to it) to infer the presence or absence of a variant that is associated with a health condition or trait.
Linkage tests are not as predictive of your dog’s true genotype as direct assays, which we use on most other genetic conditions we test for.
Traits
Explore the genetics behind your dog’s appearance and size.
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Coat Color
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Other Coat Traits
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Other Body Features
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Body Size
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.