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“Frost”
Corvus Miles to Go Before I Sleet at Wayeh

Alaskan Malamute

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American Kennel Club (AKC):

Genetic Breed Result

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Alaskan Malamute

The Alaskan Malamute is a large, fluffy spitz breed recognized as being one of the most ancient breeds of dogs. The forebears to the modern Malamute crossed the Bering Strait with their owners over 4,000 years ago. Their size, thick coat, and work drive make them ideal dogs for pulling sleds, but they also make amicable companions.

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Changes to this dog’s profile
  • On 1/30/2023 changed name from "Corvus Yet To Be Named" to "Corvus Miles to Go Before I Sleet at Wayeh"
  • On 1/12/2023 changed name from "Frost" to "Corvus Yet To Be Named"

Health Summary

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Frost has one variant that you should let your vet know about.

ALT Activity

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Frost inherited one copy of the variant we tested

Why is this important to your vet?

Frost has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Frost has this genotype, as ALT is often used as an indicator of liver health and Frost is likely to have a lower than average resting ALT activity. As such, an increase in Frost’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Factor VII Deficiency (F7 Exon 5)

Identified in Alaskan Malamutes

Day Blindness (CNGB3 Deletion, Alaskan Malamute Variant)

Identified in Alaskan Malamutes

Primary Ciliary Dyskinesia, PCD (NME5, Alaskan Malamute Variant)

Identified in Alaskan Malamutes

Alaskan Malamute Polyneuropathy, AMPN (NDRG1 SNP)

Identified in Alaskan Malamutes

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Frost’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A388

Map

A1a

Corvus Miles to Go Before I Sleet at Wayeh’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A388

Corvus Miles to Go Before I Sleet at Wayeh’s Haplotype

Part of the large A1a haplogroup, this haplotype occurs most frequently in Staffordshire Terriers, Labrador Retrievers, and English Bulldogs.

Shar Pei dogs think A1a is the coolest!

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Through Frost’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

C

Haplotype

H5a

Map

C

Corvus Miles to Go Before I Sleet at Wayeh’s Haplogroup

C is a relatively rare paternal lineage. The dog populations which bear C are a disparate bunch. The Akita and Shiba Inu are Japanese breeds, the former of which seems to have roots in the Jomon population of hunter-gatherers which were present in the islands of Japan before the ancestors of the modern Japanese arrived. The New Guinea Singing Dog, Samoyed, and Alaska Malamute are all disparate breeds that also represent the C lineage. One village dog from Peru also bore this lineage. This wide distribution and diversity suggest C is not a recently expanded lineage. It likely represents a canid lineage which diversified sometime around the Last Glacial Maximum, when the dogs of Siberia and Oceania split off and went their separate ways.

H5a

Corvus Miles to Go Before I Sleet at Wayeh’s Haplotype

Part of the C haplogroup, this haplotype occurs most commonly in Akitas and Alaskan Malamutes.

The Shiba Inu descends from this relativey rare haplogroup.

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