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Caria

American Hairless Terrier

“Nordicpearls Winter Crystal is born on the 06.01.2021 im the north of Sweden. She moved all the way to Germany with me on the 24th April and is developing into a wonderful, fearless and loving girl!”

Place of Birth

Luleå, Schweden

Current Location

Deutschland

From

Sweden

This dog has been viewed and been given 3 wags

Genetic Breed Result

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American Hairless Terrier

The American Hairless Terrier is a rare, energetic terrier breed equally adept at companionship and dog sports such as agility or barn hunt. In contrast to other hairless breeds of dog, the mutation responsible for their lack of coat is due to a recessive mutation that arose in Rat Terriers. The dog originally exhibiting this trait become the foundation for the American Hairless Terrier breed.

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Health Summary

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Caria inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Degenerative Myelopathy, DM

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Caria inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Caria’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Caria is unlikely to develop this condition due to this variant because she only has one copy of the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of her offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

ALT Activity

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Caria inherited one copy of the variant we tested

Why is this important to your vet?

Caria has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Caria has this genotype, as ALT is often used as an indicator of liver health and Caria is likely to have a lower than average resting ALT activity. As such, an increase in Caria’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Congenital Hypothyroidism (TPO, Rat, Toy, Hairless Terrier Variant)

Identified in American Hairless Terriers

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in American Hairless Terriers

Primary Lens Luxation (ADAMTS17)

Identified in American Hairless Terriers

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Caria’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A289

Map

A1b

Caria’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A289

Caria’s Haplotype

Part of the large A1b haplogroup, we have detected this haplotype most commonly in Standard Schnauzers, Rat Terriers, and Bullmastiffs.

A1b is the most common haplogroup found in German Shepherds.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Caria inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Caria is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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