AIKO inherited one copy of the variant we tested
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Changes to this dog’s profile
- On 10/21/2022 changed name from "CABERNET PINK COLLAR F" to "AIKO"
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Health Summary
AIKO is at increased risk for one genetic health condition.
Intervertebral Disc Disease (Type I)
What does this result mean?
Follow-up by our experts indicates that this genetic variant is associated with an increase to AIKO’s risk for developing Intervertebral Disc Disease (Type I).
Scientific Basis
Research studies for this variant have been based on dogs of other breeds. While dogs with similar breeds to AIKO have not yet been the focus of research studies, our data indicates that AIKO is likely to be at increased risk.
Impact on Breeding
While further investigation is warranted to determine the clinical presentation and penetrance in AIKO’s breed, we recommend taking this genetic result into account when making breeding decisions.
What is Intervertebral Disc Disease (Type I)?
Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.
Breed-Relevant Genetic Conditions
Persistent Mullerian Duct Syndrome, PMDS (AMHR2)
Identified in Miniature Schnauzers
Variant not detected
Myotonia Congenita (CLCN1 Exon 7, Miniature Schnauzer Variant)
Identified in Miniature Schnauzers
Variant not detected
Demyelinating Polyneuropathy (SBF2/MTRM13)
Identified in Miniature Schnauzers
Variant not detected
Additional Genetic Conditions
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What is a linkage test?
DNA sequences that are close together on a chromosome tend to be inherited together. Because of this, we can use genetic variation surrounding a specific variant (i.e. "linked" to it) to infer the presence or absence of a variant that is associated with a health condition or trait.
Linkage tests are not as predictive of your dog’s true genotype as direct assays, which we use on most other genetic conditions we test for.
Traits
Explore the genetics behind your dog’s appearance and size.
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Coat Color
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Other Coat Traits
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Other Body Features
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Body Size
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.