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Bourbon inherited one copy of the variant we tested
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Place of Birth
Dallas, TX, USA
Current Location
Georgia, USA
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Health Summary
Bourbon is at increased risk for one genetic health condition.
Intervertebral Disc Disease (Type I)
How to interpret this result
Bourbon has one copy of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.
What is Intervertebral Disc Disease (Type I)?
Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.
Breed-Relevant Genetic Conditions
5 variants not detected
Von Willebrand Disease Type I, Type I vWD (VWF)
Identified in Small Poodles
Variant not detected
Progressive Retinal Atrophy, prcd (PRCD Exon 1)
Identified in Small Poodles
Variant not detected
GM2 Gangliosidosis (HEXB, Poodle Variant)
Identified in Small Poodles
Variant not detected
Neonatal Encephalopathy with Seizures, NEWS (ATF2)
Identified in Small Poodles
Variant not detected
Osteochondrodysplasia (SLC13A1, Poodle Variant)
Identified in Small Poodles
Variant not detected
Additional Genetic Conditions
206 variants not detected
