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“Ugo”
Avitus Count Ugo Carnifex Di Windypine

Cane Corso

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Place of Birth

Blackfalds, AB, Canada

Current Location

Charlotte, North Carolina, USA

From

Cheyenne, WY, USA

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Registration

American Kennel Club (AKC): WS54737908

Genetic Breed Result

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Cane Corso

Cane Corsos are strong working dogs, also acting as loyal and protective companion dogs.

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Health Summary

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Ugo has one variant that you should let your vet know about.

ALT Activity

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Ugo inherited one copy of the variant we tested

Why is this important to your vet?

Ugo has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Ugo has this genotype, as ALT is often used as an indicator of liver health and Ugo is likely to have a lower than average resting ALT activity. As such, an increase in Ugo’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Canine Multifocal Retinopathy, cmr1 (BEST1 Exon 2)

Identified in Cane Corsos

Additional Genetic Conditions

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Traits

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Coat Color

Coat Color

Other Coat Traits

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Performance

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Through Ugo’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A410

Map

A1b

Avitus Count Ugo Carnifex Di Windypine’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A410

Avitus Count Ugo Carnifex Di Windypine’s Haplotype

Part of the A1b haplogroup, the A410 haplotype occurs most commonly in Cimarron Uruguayos and Small Poodles.

A1b is the most common haplogroup found in German Shepherds.

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Through Ugo’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

D

Haplotype

H7.1/6/7

Map

D

Avitus Count Ugo Carnifex Di Windypine’s Haplogroup

The D paternal lineage is very common in well-known populations of dogs. Breeds belonging to the D lineage likely have direct male ancestors that can be traced all the way back to the origin of domestic dogs themselves! One popular breed that commonly sports a D lineage is the Boxer. Boxers were developed in the late 19th century from Mastiff dogs, so it is no surprise that D is well represented among Mastiffs, Bulldogs, as well as Terriers. Intriguingly, D is also found among Lhasa Apsos, an ancient Tibetan breed, and Afghan Hounds. While the presence of this lineage in Polynesia or the New World can be chalked up to interbreeding with European dogs brought during voyages of discovery or later settlement, D is also well represented among village dog populations in the Middle East and Africa. If the fact that we find dogs bearing a D lineage in the Middle East (not to mention the large amount of diversity among Middle Eastern D lineage males) is any indication of ancient residence in that region, then the presence among Oceanian village dogs is peculiar. Rather, it may be that D is part of a broader Eurasian group of ancient paternal lineages which disappeared from the eastern portion of its original range, persisting in the island of New Guinea as well as West Asia and Africa. With the rise of Mastiff breeds, the D lineage received a new life as it became common among many types of working dogs.

H7.1/6/7

Avitus Count Ugo Carnifex Di Windypine’s Haplotype

Part of the D haplogroup, this haplotype occurs most frequently in mixed breed dogs.

The D paternal lineage is common in Boxers.

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